Product Name: GHRP-2 (Growth Hormone Releasing Peptide-2)3

Quantity: 5mg (Lyophilized Powder)4

CAS Number: 158861-67-7

Overview

GHRP-2, also known as Pralmorelin, is a first-generation synthetic peptide composed of six amino acids (a hexapeptide).⁵ It is classified as a potent growth hormone secretagogue (GHS) and is one of the most widely researched peptides in its class.⁶ It functions primarily as an agonist of the ghrelin/growth hormone secretagogue receptor (GHSR-1a).⁷

Mechanism of Action

GHRP-2’s primary mechanism involves mimicking the action of ghrelin, the body’s natural “hunger hormone,” which also plays a key role in regulating energy balance and GH release.⁸

• Pituitary Stimulation: It binds directly to GHSR-1a receptors in the anterior pituitary gland, signaling the somatotroph cells to produce and release endogenous growth hormone.⁹

• Hypothalamic Action: GHRP-2 also acts on the hypothalamus to amplify the natural GHRH (Growth Hormone-Releasing Hormone) signal.¹⁰

• Somatostatin Inhibition: It actively suppresses somatostatin, a hormone that inhibits the release of growth hormone.¹¹ This dual action of stimulating GH release while reducing its inhibition makes GHRP-2 a very effective tool for research into GH pulsation.

Unlike its counterpart, GHRP-6, GHRP-2 is known for stimulating a more intense release of GH with less pronounced effects on appetite or cortisol/prolactin levels at standard research doses.

Product Specifications

• Purity: >98% (as determined by HPLC)

• Appearance: Sterile, white lyophilized (freeze-dried) powder¹²

• Molecular Formula: ¹³$C_{45}H_{55}N_{9}O_{6}$

• Molecular Weight: 817.9 g/mol¹⁴

• Sequence: D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2¹⁵

• Storage: Store at 2°C to 8°C. For long-term storage, -20°C is recommended.¹⁶

Disclaimer

This product is sold as 5mg of lyophilized powder in a sealed vial. It is intended strictly for laboratory and research use only. It is not for human consumption, therapeutic, or diagnostic use. Reconstitution with bacteriostatic or sterile water is required before research application.