Product Name: GHRP-6 (Growth Hormone Releasing Peptide-6)

Quantity: 10mg (Lyophilized Powder)

CAS Number: 87616-84-03

Overview

GHRP-6 is a first-generation synthetic hexapeptide (a peptide chain of six amino acids) with the sequence His-D-Trp-Ala-Trp-D-Phe-Lys-NH2. It is one of the most well-known and extensively researched growth hormone secretagogues (GHS) available for laboratory study.

Mechanism of Action

GHRP-6’s primary function is to mimic the action of ghrelin, the body’s endogenous “hunger hormone.” It acts as a synthetic agonist for the growth hormone secretagogue receptor (GHSR-1a), which is found in the anterior pituitary gland and hypothalamus.

• Pituitary Stimulation: It binds directly to these receptors, signaling the pituitary gland to produce and release a strong, pulsatile burst of endogenous growth hormone (GH).

• Ghrelin Mimetic: By activating the ghrelin receptor, GHRP-6 is a potent simulator of appetite (an orexigenic agent). This makes it a key subject of research for its effects on metabolism, food intake, and energy balance.

• Somatostatin Inhibition: GHRP-6 also amplifies the GH pulse by suppressing somatostatin (Growth Hormone-Inhibiting Hormone), a peptide that normally acts as a “brake” on GH release.

Compared to other GHRPs, GHRP-6 is particularly distinguished by its significant impact on increasing hunger and gastric motility.

Product Specifications

• Purity: >98% (as determined by HPLC)

• Appearance: Sterile, white lyophilized (freeze-dried) powder

• Molecular Formula: ⁹$C_{46}H_{56}N_{12}O_{6}$

• Molecular Weight: 873.0 g/mol

• Storage: Store at 2°C to 8°C. For long-term storage, -20°C is recommended.

Disclaimer

This product is sold as 10mg of lyophilized powder in a sealed vial. It is intended strictly for laboratory and research use only. It is not for human consumption, therapeutic, or diagnostic use. Reconstitution with bacteriostatic or sterile water is required before research application.