Sermorelin is a research peptide that represents the 1-29 amino acid fragment of human growth hormone-releasing hormone (GHRH), making it the shortest fully functional fragment of endogenous GHRH. Its primary mechanism of action involves binding to and activating the growth hormone-releasing hormone receptor (GHRHR) located in the pituitary gland.

This stimulation promotes the body’s own natural synthesis and pulsatile release of growth hormone (GH). Unlike direct administration of synthetic human growth hormone, Sermorelin works by supporting the natural endocrine pathway. It is widely used in research to investigate pituitary function, the effects of GHRH stimulation, and the downstream physiological processes regulated by GH, such as metabolism, cell regeneration, and body composition.

• CAS Number: 86168-78-7