Product Name: CJC-1295 without DAC (Modified GRF 1-29) Quantity: 10mg (Lyophilized Powder) CAS Number: 863288-34-0

Overview

CJC-1295 without DAC is a 29-amino acid synthetic peptide and a modified analogue of Growth Hormone-Releasing Hormone (GHRH). It is also known in research circles as Modified GRF (1-29). The “Modified” designation refers to four specific amino acid substitutions within its chain, which were engineered to provide stability and protect the peptide from rapid enzymatic degradation, primarily by dipeptidyl peptidase-IV (DPP-IV).

Mechanism of Action

As a GHRH analogue, Mod GRF (1-29) functions by binding to and stimulating GHRH receptors on the anterior pituitary gland. This action signals the pituitary to synthesize and release the body’s own endogenous growth hormone (GH).

Key Feature: “Without DAC”

The defining characteristic of this product is the absence of the Drug Affinity Complex (DAC).

• Pulsatile Release: Unlike the long-acting DAC version, CJC-1295 without DAC has a very short active half-life, estimated to be around 30 minutes.

• Biomimetic Function: This short duration of action is ideal for research protocols aiming to replicate the natural, pulsatile (or wave-like) secretion pattern of growth hormone, rather than inducing a prolonged, sustained elevation of GH levels.

Product Specifications

• Purity: >98% (Confirmed by HPLC)

• Appearance: Sterile, white lyophilized (freeze-dried) powder in a sealed vial.

• Storage: For optimal integrity, store lyophilized powder at 2°C to 8°C. For long-term storage, -20°C is recommended.

For Research Use Only

This product is supplied as 10mg of sterile, lyophilized powder. It is intended strictly for in vitro laboratory and research use only. It is not for human consumption, therapeutic, or diagnostic applications. Reconstitution with a suitable solvent (such as bacteriostatic water) is required before use.