Product Name: GHRP-6 (Growth Hormone Releasing Peptide-6)

Quantity: 5mg (Lyophilized Powder)3

CAS Number: 87616-84-04

Overview

GHRP-6 is a first-generation synthetic hexapeptide (a peptide chain of six amino acids) with the sequence His-D-Trp-Ala-Trp-D-Phe-Lys-NH2.⁵ It is one of the most well-known and widely studied growth hormone secretagogues (GHS).⁶

Mechanism of Action

GHRP-6 functions as a synthetic agonist of the growth hormone secretagogue receptor (GHSR-1a), the same receptor activated by the endogenous “hunger hormone,” ghrelin.⁷ Its mechanism is distinct from that of GHRH (Growth Hormone-Releasing Hormone).

• Pituitary Stimulation: It acts directly on the anterior pituitary gland to stimulate the synthesis and pulsatile release of endogenous growth hormone (GH).⁸

• Ghrelin Mimetic: By mimicking ghrelin, GHRP-6 is a potent simulator of appetite (an orexigenic agent) and is often researched for its effects on metabolism, food intake, and energy balance.⁹

• Somatostatin Inhibition: Like GHRP-2, it also helps amplify the GH pulse by suppressing somatostatin, a hormone that inhibits the release of growth hormone.

Compared to other GHRPs (like GHRP-2), GHRP-6 is particularly noted for its significant impact on increasing hunger and gastric motility.

Product Specifications

• Purity: >98% (as determined by HPLC)

• Appearance: Sterile, white lyophilized (freeze-dried) powder¹⁰

• Molecular Formula: ¹¹$C_{46}H_{56}N_{12}O_{6}$

• Molecular Weight: 873.0 g/mol¹²

• Storage: Store at 2°C to 8°C.¹³ For long-term storage, -20°C is recommended.

Disclaimer

This product is sold as 5mg of lyophilized powder in a sealed vial. It is intended strictly for laboratory and research use only. It is not for human consumption, therapeutic, or diagnostic use. Reconstitution with bacteriostatic or sterile water is required before research application.