IGF-1 LR3 (Long Arginine 3-IGF-1) is a synthetic, recombinant analog of human Insulin-like Growth Factor-1 (IGF-1). This 0.1mg product is supplied as a sterile, white lyophilized (freeze-dried) powder intended for research and laboratory use.

This analog is structurally modified from the native 70-amino-acid IGF-1 to enhance its biological properties. It consists of 83 amino acids with two key modifications:

1. “LR3” (Long Arginine 3): A substitution of an Arginine (R) for the Glutamic Acid (E) at the third amino acid position.

2. “Long”: A 13-amino-acid extension at the N-terminus.

These changes result in a protein with a significantly lower affinity for Insulin-like Growth Factor-Binding Proteins (IGFBPs). Because IGFBPs normally sequester and inactivate IGF-1, this modification dramatically increases the molecule’s active half-life and potency, making it approximately three times more potent than native IGF-1.

It is a powerful supplement for serum-free or low-serum cell culture media, widely used to promote the proliferation and differentiation of various cell types in biopharmaceutical research.

• Product: IGF-1 LR3

• Quantity: 0.1mg (100mcg)

• Appearance: White Lyophilized Powder

• Purity: Typically ≥95% (as determined by HPLC)

• CAS Number: 143045-27-6

• Storage: Store lyophilized powder at -20°C. Once reconstituted, store at 2-8°C for short-term use or -20°C for long-term storage. Avoid repeated freeze-thaw cycles.

• Intended Use: This product is sold for research use only (RUO) and is not intended for human consumption or diagnostic/therapeutic procedures.